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Antigenic Specificity | INPP5B (C-term), 950-979 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This INPP5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 950-979 amino acids from the C-terminal region of human INPP5B. Cellular calcium signaling is controlled by the productionof inositol phosphates (IPs) by phospholipase C in response toextracellular signals. The IP signaling molecules are inactivatedby a family of inositol polyphosphate-5-phosphatases(5-phosphatases). INPP5B encodes the type II 5-phosphatase. Theprotein is localized to the cytosol and mitochondria, andassociates with membranes through an isoprenyl modification nearthe C-terminus. Several alternatively spliced transcript variantsof this gene have been described, but the full-length nature of |
Immunogen | n/a |
Other Names | [Type II inositol 1,5-trisphosphate 5-phosphatase; 75 kDa inositol polyphosphate-5-phosphatase; Phosphoinositide 5-phosphatase; 5PTase; INPP5B; OCRL2] |
Gene, Accession # | [INPP5B], Gene ID: 3633, NCBI: NP_005531.2, UniProt: P32019 |
Catalog # | MBS9214584 |
Price | $165, $370 |
Order / More Info | INPP5B (C-term), 950-979 Antibody from MYBIOSOURCE INC. |
Product Specific References | Coon, B.G., et al. Hum. Mol. Genet. 18(23):4478-4491(2009) Mao, Y., et al. EMBO J. 28(13):1831-1842(2009) Williams, C., et al. J. Cell. Sci. 120 (PT 22), 3941-3951 (2007) : Speed, C.J., et al. Eur. J. Biochem. 234(1):216-224(1995) Janne, P.A., et al. Genomics 28(2):280-285(1995) |