SHANK2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SHANK2 |
| Clone | [S23b-6] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | APC-Cy7 conjugate |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Antibody Microarray (AM) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~160 kDa. No cross-reactivity against Shank1 or Shank3. Weak mouse detection. Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins (1). Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Studies suggest that Shank2 is expressed in the neurons of the developing retina, and could play a role in the neuronal differentiation of the developing retina (2). Other recent studies suggest that the disruption of glutamate receptors at the Shank postsynaptic platform could contribute to the destruction of the postsynaptic density, which underlies the synaptic dysfunction and loss in Al |
| Immunogen | Immunogen: Fusion protein amino acids 84-309 (SH3/PDZ domains) of rat Shank2 (SH3 and multiple ankyrin repeat domains protein 2) |
| Other Names | [Mouse Rat SHANK2 IgG1; SHANK2 : APC/Cy7; Shank2; PROSAP1; cortactin binding protein 1; KIAA1022; AUTS17; CortBP1; Proline-rich synapse-associated protein 1; SH3 and multiple ankyrin repeat domains protein 2; Cortactin-binding protein 1; proline-rich synapse associated protein 1; SPANK-3; GKAP/SAPAP interacting protein; SHANK; cortactin SH3 domain-binding protein; ProSAP1; CORTBP1CTTNBP1; SH3 and multiple ankyrin repeat domains 2] |
| Gene, Accession # | [SHANK2], Gene ID: 171093, NCBI: NP_958738.1, UniProt: Q9QX74 |
| Catalog # | MBS8002914 |
| Price | $510 |
| Order / More Info | SHANK2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Sheng M., and Kim E. (2000) Journal of Cell Science. 113: 1851-1856. 2. Kim J.H., et al. (2009) Exp Mol Med. 41(4): 236-242. 3. Gong Y., et al. (2009) Brain Res. 1292: 191-198. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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