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Antigenic Specificity | Caspase-10 B/C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Caspase-10 B/C Polyclonal Antibody detects endogenous levels of Caspase-10 B/C protein. CASP10 encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in CASP10 are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcr |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human Caspase-10 B/C at AA range: 400-480 |
Other Names | [Rabbit Caspase-10 B/C; ALPS2; apoptotic protease Mch-4; CASPA; caspase-10; FADD-like ICE2; FAS-associated death domain protein interleukin-1B-convert] |
Gene, Accession # | [CASP-10], Gene ID: 843, NCBI: NP_001193453.1, UniProt: Q92851 |
Catalog # | MBS9701580 |
Price | $130, $220, $325 |
Order / More Info | Caspase-10 B/C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |