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Antigenic Specificity | DARPP-32 (Phospho Thr34) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-DARPP-32 (T34) Polyclonal Antibody detects endogenous levels of DARPP-32 protein only when phosphorylated at T34. PPP1R1B encodes a bifunctional signal transduction molecule (protein phosphatase 1 regulatory inhibitor subunit 1B). Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, PPP1R1B may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for PPP1R1B. |
Immunogen | Immunogen: Synthesized peptide derived from human DARPP-32 around the phosphorylation site of T34 |
Other Names | [Rabbit DARPP-32 (phospho Thr34); PPP1R1B; DARPP32; Protein phosphatase 1 regulatory subunit 1B; DARPP-32; Dopamine-and cAMP-regulated neuronal phosphoprotein] |
Gene, Accession # | [DARPP-32], Gene ID: 84152, NCBI: NP_001229393.1, UniProt: Q9UD71 |
Catalog # | MBS9701262 |
Price | $130, $220, $325 |
Order / More Info | DARPP-32 (Phospho Thr34) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |