Stat5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityStat5
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.5 mg/ml
ApplicationsWestern Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC)
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DescriptionBackground: Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-alpha and form a heterodimer which is part of the ISGF3 transcription factor complex. Althomugh early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3beta appears to be activated by both while Stat3alpha is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 is activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
ImmunogenImmunogen: Synthetic peptide surrounding amino acid 777 of human Stat5. Positive Control: Western Blot: 3T3 cell lysate and rat Kideny tissue lysate. IHC: Breast tissue
Other Names[Signal transducer and activator of transcription 5; stat -5; STAT5; STAT-5; STAT 5], [STAT5B; STAT5B; STAT5]
Gene, Accession #[Stat5], Gene ID: 6777, NCBI: NP_036580.2, UniProt: P51692
Catalog #MBS841375
Price$150, $290
Order / More InfoStat5 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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