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Antigenic Specificity | IkappaB beta |
Clone | [3H3-6E9-9H9] |
Host Species | Mouse |
Reactive Species | human, rat, mouse |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. |
Immunogen | Immunogen: Purified recombinant protein expressed in E Coli. |
Other Names | [I kappa b beta; NFKBIB; TRIP9] |
Gene, Accession # | [IKB], Gene ID: 4793, NCBI: NP_001230045.1, UniProt: Q15653 |
Catalog # | MBS8539903 |
Price | $280 |
Order / More Info | IkappaB beta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |