Estrogen Receptor (1D5), ESR1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Estrogen Receptor (1D5), ESR1 |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 5 mL |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody is used for the detection of oestrogen receptors in normal and diseased tissue, especially in mamma carcinoma and metastases. The amount of oestrogen receptors may be helpful for decision making in anti-hormone therapy and evaluation of prognosis in mamma carcinoma. It should always be used in combination with other markers like progesterone receptor, cathepsin D, C-erbB-2 and other relevant clinical information. Tissues which are stimulated by oestrogens require receptors for these steroid hormones. Oestrogen receptor alpha (ESR1) is mainly located in the nuclei of the responsive tissues, but to a minor extent also in the cytoplasm. Oestrogen responsive tissues are especially epithelial cells of the myometrium of the uterus an |
| Immunogen | Immunogen: Recombinant human estrogen receptor alpha (ESR1) |
| Other Names | [estrogen receptor, partial; Estrogen receptor; estrogen receptor; estrogen receptor 1; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1], [ESR1; ESR1; ER; ESR; Era; ESRA; ESTRR; NR3A1; ESR; NR3A1; ER] |
| Gene, Accession # | Gene ID: 2099, NCBI: AAC51875.1 |
| Catalog # | MBS397296 |
| Price | $455 |
| Order / More Info | Estrogen Receptor (1D5), ESR1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Al Saati T., Clamens S., Cohen-Knafo E., Faye J.C., Prats H., Coindre J.M., et al. (1993) Production of monoclonal antibodies to human estrogen receptor protein (ER) using recombinant ER (RER). Int. J. Cancer 55; 651-654. 2. Sannino P. and Shousha S. (1994) Demonstration of oestrogen receptors in paraffin wax sections of breast carcinoma using the monoclonal antibody 1D5 and microwave oven processing. J. Clin. Pathol. 47; 90-92. 3. Mauri F.A., Veronese S., Frigo B., Girlando S., Losi L., Gambocorta M., et al. (1994) ER 1D5 and H222 (ER-ICA) antibodies to human estrogen receptor protein in breast carcinomas. Results of a multicentric comparative study. Appl. Immunohistochem. 2; 157-163. 4. Barnes D.M., Harris W.H., Smith P., Millis R.R., and Rubens R.D. (1996) Immunohistochemical determination of oestrogen receptor: comparison of different methods of assessment of staining and correlation with clinical outcome of breast cancer patients. Br. J. Cancer 74; 1445-1451. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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