ECSIT Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityECSIT
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formation exchange purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionECSIT Antibody: Activation of NF-κB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses. Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6. ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possi
ImmunogenImmunogen: ECSIT antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT. Buffer: ECSIT Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[ECSIT; SITPEC; Evolutionarily conserved signaling intermediate in Toll pathway; mitochondrial; Protein SITPEC; ECSIT homolog (Drosophila)], [ECSIT; ECSIT; SITPEC]
Gene, Accession #[ECSIT], Gene ID: 51295, NCBI: NP_057665, UniProt: Q9BQ95
Catalog #MBS151285
Price$375
Order / More InfoECSIT Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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