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Antigenic Specificity | ECSIT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ECSIT Antibody: Activation of NF-κB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses. Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6. ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possi |
Immunogen | Immunogen: ECSIT antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT. Buffer: ECSIT Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ECSIT; SITPEC; Evolutionarily conserved signaling intermediate in Toll pathway; mitochondrial; Protein SITPEC; ECSIT homolog (Drosophila)], [ECSIT; ECSIT; SITPEC] |
Gene, Accession # | [ECSIT], Gene ID: 51295, NCBI: NP_057665, UniProt: Q9BQ95 |
Catalog # | MBS151285 |
Price | $375 |
Order / More Info | ECSIT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |