Phospho-Nephrin (Tyr1176) ? Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-Nephrin (Tyr1176) ? |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mousepredicted: porcine, bovine, horse, sheep, rabbit, dog |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Peptide ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-Nephrin(Tyr1176) Antibody detects endogenous levels of Nephrin only when phosphorylated at Tyr1176. Description: Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity).Post Translational Modifications: Phosphorylated at Tyr-1193 by FYN, leading to the recruitment and activation of phospholipase C-gamma-1/PLCG1.Subunit Structure: Interacts with CD2AP (via C-terminal domain). Interacts with MAGI1 (via PDZ 2 and 3 domains) forming a tripartite complex with IGSF5/J |
| Immunogen | Immunogen: A synthesized peptide derived from human Nephrin around the phosphorylation site of Tyr1176. Tissue Specificity: Specifically expressed in podocytes of kidney glomeruli. |
| Other Names | [CNF; Nephrin; Nephrosis 1 congenital Finnish type; Nephrosis 1, congenital, Finnish type (nephrin); NPHN_HUMAN; NPHS 1; Nphs1; Renal glomerulus specific cell adhesion receptor; Renal glomerulus-specific cell adhesion receptor] |
| Gene, Accession # | [NPHN], Gene ID: 4868, NCBI: AAG17141.1, UniProt: O60500 |
| Catalog # | MBS9610813 |
| Price | $225, $280, $340 |
| Order / More Info | Phospho-Nephrin (Tyr1176) ? Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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