Human VEGFR-2/KDR (Peptide), soluble Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human VEGFR-2/KDR (Peptide), soluble |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis. |
| Immunogen | Immunogen: Peptide: CGRETILDHSAEAVGMP. Preparation: Produced from sera of rabbits pre-immunized with a peptide consisting of the unique C-terminal end of esKDR: CGRETILDHSAEAVGMP. |
| Other Names | [human endogenous soluble VEGFR-2/KDR; Vascular endothelial growth factor receptor 2; Protein-tyrosine kinase receptor flk-1], [KDR; KDR; FLK1; CD309; VEGFR; VEGFR2; FLK1; VEGFR2; VEGFR-2; FLK-1; KDR] |
| Gene, Accession # | [VEGFR-2/KDR], Gene ID: 3791, NCBI: NP_002244.1, UniProt: P22333 |
| Catalog # | MBS691047 |
| Price | $280 |
| Order / More Info | Human VEGFR-2/KDR (Peptide), soluble Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Shibata et al, BMC Medicine 8 (2010) 2. Albaquerque et al, Nature Med 2009 3. Ebos et al, Mol Cancer Res 2 (2004) 4. Ebos et al, Cancer res 68 (2008). |
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