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Antigenic Specificity | FBL (Center E120), 105-135 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This FBL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-135 amino acids from the Central region of human FBL. FBL is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. This protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scle |
Immunogen | n/a |
Other Names | [rRNA 2'-O-methyltransferase fibrillarin; 211-; 34 kDa nucleolar scleroderma antigen; Histone-glutamine methyltransferase; FBL; FIB1; FLRN] |
Gene, Accession # | [FBL], Gene ID: 2091, NCBI: NP_001427.2, UniProt: P22087 |
Catalog # | MBS9215080 |
Price | $165, $370 |
Order / More Info | FBL (Center E120), 105-135 Antibody from MYBIOSOURCE INC. |
Product Specific References | Amin,M.A., Biochem. Biophys. Res. Commun. 360 (2), 320-326 (2007) Dunphy,J.L., Traffic 8 (6), 661-672 (2007) |