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Antigenic Specificity | PRUNE2 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene belongs to the B-cell CLL/lymphoma 2 and adenovirus E1B 19 kDa interacting family, whose members play roles in many cellular processes including apotosis, cell transformation, and synaptic function. Several functions for this protein have been demonstrated including suppression of Ras homolog family member A activity, which results in reduced stress fiber formation and suppression of oncogenic cellular transformation. A high molecular weight isoform of this protein has also been shown to colocalize with Adaptor protein complex 2, beta-Adaptin and endodermal markers, suggesting an involvement in post-endocytic trafficking. In prostate cancer cells, this gene acts as a tumor suppressor and its expression is re |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PRUNE2 |
Other Names | [protein prune homolog 2 isoform 2; Protein prune homolog 2; protein prune homolog 2; prune homolog 2 with BCH domain; BNIP2 motif-containing molecule at the C-terminal region 1] |
Gene, Accession # | [PRUNE2], Gene ID: 158471, NCBI: NP_001294976.1, UniProt: Q8WUY3 |
Catalog # | MBS3222634 |
Price | $335 |
Order / More Info | PRUNE2 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |