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Antigenic Specificity | Interleukin 13 receptor, alpha 1, IL13Ralpha1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1), is a human gene. The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. The protein had 76% homology to murine IL13R-alpha, with 95% amino acid identity in the cytoplasmic domain.1 IL-13 receptor alpha chain (NR4) is the primary binding subunit of the IL-13 receptor and may also be a component of IL-4 receptors.2 IL-13Ra1 has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.3 |
Immunogen | Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the region of IL13Rα1. |
Other Names | [Interleukin 13 receptor; alpha 1; IL13Ralpha1; Interleukin 13 receptor; alpha 1; IL13Ra1], [IL13RA1; IL13RA1; NR4; CD213A1; IL-13Ra; IL13R; IL13RA; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; CT19] |
Gene, Accession # | [IL13Ralpha1], Gene ID: 3597, NCBI: AAH15768.1, UniProt: P78552 |
Catalog # | MBS355052 |
Price | $275 |
Order / More Info | Interleukin 13 receptor, alpha 1, IL13Ralpha1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Aman, M. J., Tayebi, N., Obiri, N. I., Puri, R. K., Modi, W. S., Leonard, W. J. cDNA cloning and characterization of the human interleukin 13 receptor alpha chain. J. Biol. Chem. 271: 29265-29270, 1996. 2. Hilton, D. J., Zhang, J.-G., Metcalf, D., Alexander, W. S., Nicola, N. A., Willson, T. A. Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc. Nat. Acad. Sci. 93: 497-501, 1996. 3. Entrez Gene: IL13RA1 interleukin 13 receptor, alpha 1. |