CDH1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CDH1 |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse, monkey |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | E-Cadherin is a 120 kDa transmembrane glycoprotein that is localized in the adherens junctions of epithelial cells. There, it interacts with the cytoskeleton through the associated cytoplasmic catenin proteins. In addition to being a calcium-dependent adhesion molecule, E-Cadherin is also a critical regulator of epithelial junction formation. Its association with catenins is necessary for cell-cell adhesion. These E-cadherin/catenin complexes associate with corical actin bundles at both the zonula adherens and the lateral adhesion plaques. Tyrosine phosphorylation can disrupt these complexes, leading to changes in cell adhesion properties. E-Cadherin expression is often down-regulated in highly invasive, poorly differentiated carcinomas. In |
| Immunogen | Immunogen: Purified recombinant fragment of human CDH1 expressed in E. Coli. |
| Other Names | [UVO; CDHE; ECAD; LCAM; Arc-1; CD324; CDH1], [CDH1; CDH1; UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324; CDHE; UVO; E-cadherin] |
| Gene, Accession # | [CDH1], Gene ID: 999, NCBI: NP_004351.1, UniProt: P12830 |
| Catalog # | MBS850097 |
| Price | $280 |
| Order / More Info | CDH1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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