PECAM-1, Mouse Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PECAM-1, Mouse |
| Clone | ER-MP12 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | F, Flow Cytometry (FC/FACS), Immunoassay (IA), Immunoprecipitation (IP), P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody ER-MP12 recognizes mouse platelet endothelial cell adhesion molecule-1 (PECAM-1;CD31). PECAM-1 is a 130kDa glycoprotein involved in- cell adhesion and a signalling receptor that is expressed on hematopoietic and endothelial cells. It is a member of the immunoglobulin (Ig)-superfamily of cell adhesion molecules. The type I transmembrane protein is composed of an extracellular region of six Ig-like homology domains, a 19-residue transmembrane domain, and a 118 residue cytoplasmic tail and is differentially glycosylated involving N-linked and O-linked glycosylation sites. The signalling of PECAM-1 is based on 2 immuno receptor tyrosine inhibitory motifs (ITIMs) in its cytoplasmic domain. These ITIM |
| Immunogen | Immunogen: Mouse macrophage precursor hybrid cells. W1C31 |
| Other Names | [Platelet endothelial cell adhesion molecule-1; CD31; EndoCam], [PECAM1; PECAM1; CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM; PECAM-1] |
| Gene, Accession # | [PECAM-1], Gene ID: 5175, NCBI: AAA36429.1 |
| Catalog # | MBS584140 |
| Price | $420 |
| Order / More Info | PECAM-1, Mouse Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Leenen, P et al; Murine macrophage precursor characterization II. Monoclonal antibodies against macrophage precursor antigens. Eur J Immunol 1990, 20: 27 2. De Bruijn, M et al; Distinct mouse bone marrow macrophage precursors identified by differential expression of ER-MP12 and ER-MP20 antigens. Eur J Immunol 1994, 24: 2279 3. Morioka, Y et al; Immunophenotypic and ultrastructural heterogeneity of macrophage differentiation in bone marrow and fetal hematopoiesis of mouse in vitro and in vivo. J Leukoc Biol 1994, 55: 642 4. Ling, V et al; Structural identification of the hematopoeitic progenitor antigen ER-MP12 as the vascular endothelial adhesion molecule PECAM-1 (CD31). Eur J Immunol 1997, 27: 509 5. De Bruijn, M et al; Bone marrow cellular composition in Listeria monocytogenes infected mice detected using ER-MP12 and ER-MP20 antibodies: a flow cytometric alternative to differential counting. J Immunol Methods 1998, 217: 27 6. Van Rijt, L et al. Allergen-induced accumulation of airway dendritic cells is supported by an increase in CD31hiLy-6Cneg bone marrow precursors in a mouse model of athma. Blood 2002, 100 :3663 7. Jin, M et al. Enhancement of repopulation and hematopoiesis of bone marrow cells in irradiated mice by oral administration of PG101, a water-soluble extract from Lentinus lepideus. Exp biol med- 2003, 228 :759 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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