p53 Antibody from MYBIOSOURCE INC.

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Antigenic Specificityp53
Clone[PAb122]
Host SpeciesMouse
Reactive Specieshuman, monkey, dog, mouse, rat, hamster.
IsotypeIgG2b, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
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DescriptionRecognizes a conserved determinant of the p53 protein. Its epitope maps near the C-terminus end (aa 370-378) of p53. It has been used successfully to immunoprecipitate p53 oncoprotein complexes with simian virus 40 (SV40) large T antigen. Reportedly, this antibody precipitated the most ATPase-active form of T. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
ImmunogenImmunogen: SV40-transformed mouse B4 cells Quantity and Buffer: 0.5 ml at 200ug/ml with BSA and azide
Other Names[Antigen NY-CO-13; BCC7; Cellular Tumor Antigen p53; LFS1; TP53; Transformation Related Protein 53 (TRP53); Tumor Protein p53; Tumor Suppressor p53], [TP53; TP53; P53; BCC7; LFS1; TRP53; P53]
Gene, Accession #[TP53], Gene ID: 7157, NCBI: NP_000537.3, UniProt: P04637
Catalog #MBS438187
Price$190, $340, $340
Order / More Infop53 Antibody from MYBIOSOURCE INC.
Product Specific References1. Gurney EG et. al. Journal of Virology, 1980, 34(3):752-63.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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