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Antigenic Specificity | SOCS2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
Immunogen | Immunogen: Recombinant Human Suppressor of cytokine signaling 2 protein (1-198AA) Conjugation: Non-conjugated |
Other Names | [Suppressor of cytokine signaling 2; SOCS-2; Cytokine-inducible SH2 protein 2; CIS-2; STAT-induced STAT inhibitor 2; SSI-2; SOCS2; CIS2; SSI2; STATI2] |
Gene, Accession # | [SOCS2], Gene ID: 8835, NCBI: NP_001257396.1, UniProt: O14508 |
Catalog # | MBS7052413 |
Price | $160, $235 |
Order / More Info | SOCS2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |