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Antigenic Specificity | HMG14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HMG14 antibody detects endogenous levels of total HMG14. Function: Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity).Post-translational Modifications: Phosphorylation on Ser-21 and Ser-25 weakens binding to nucleosomes and increases the rate of H3 phosphorylation (By similarity). Phosphorylation favors cytoplasmic localization.Similarity: Belongs to the HMGN family. |
Immunogen | Immunogen: A synthesized peptide derived from human HMG14 Subcellular Location: Nucleus. Cytoplasm. Cytoplasmic enrichment upon phosphorylation. The RNA edited version localizes to the nucleus. Predicted Cross Reactivity: Pig, Bovine, Horse, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Dog (100%), Chicken (100%), Xenopus (100%) |
Other Names | [FLJ27265; FLJ31471; High mobility group (nonhistone chromosomal) protein 14; High mobility group nucleosome binding 1; High mobility group nucleosome binding domain 1; High mobility group nucleosome binding domain containing protein 1; High mobility group nucleosome-binding domain-containing protein 1; High mobility group protein 14; HMG 14; HMG14; HMGN 1; HMGN1; HMGN1_HUMAN; MGC104230; MGC117425; Non-histone chromosomal protein HMG-14; Nonhistone chromosomal protein HMG 14; Nonhistone chromosomal protein HMG14] |
Gene, Accession # | [HMG14], Gene ID: 3150, NCBI: NP_004956.5, UniProt: P05114 |
Catalog # | MBS9609094 |
Price | $240, $280 |
Order / More Info | HMG14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |