DNMT3a Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DNMT3a |
| Clone | [ABM13G4] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Dnmt3a belongs to the mammalian methyltransferase gene family which is responsible for tissue-specific gene expression. Dnmt3a together with other methyltransferases conducts de novo methylation of cytosine residues in CpG islands by the enzymatic addition of methyl residues from S-adenosyl-L-methionine to the 5-carbon atom of the cytosine ring. Dnmt3a also directs a metabolic program by repressing key genes to enable the coupling of insulin secretion to glucose levels during beta cell maturation. Loss of Dnmt3a in pancreatic beta cells prevents this developmental metabolic reprogramming, resulting in loss of GSIS (Glucose-Stimulated Insulin Secretion)). Dnmt3a overexpression has been found in several cancers including AML (Acute Myeloid Le |
| Immunogen | Immunogen Information: A partial length recombinant protein from DNMT3a was used as the immunogen for this antibody. |
| Other Names | [DNA (cytosine-5)-methyltransferase 3A; DNA methyltransferase HsaIIIA; DNA MTase HsaIIIA; M.HsaIIIA], [DNMT3A; DNMT3A; TBRS; DNMT3A2; M.HsaIIIA; Dnmt3a; DNA MTase HsaIIIA; M.HsaIIIA] |
| Gene, Accession # | [DNMT3A], Gene ID: 1788, NCBI: Q9Y6K1.4, UniProt: Q9Y6K1 |
| Catalog # | MBS668324 |
| Price | $290 |
| Order / More Info | DNMT3a Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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