LCK Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LCK |
| Clone | [845CT3.5.2] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | ascites |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Purified His-tagged LCK protein was used to produced this monoclonal antibody. Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein to the vicinity of the TCR/CD3 complex. LCK then phosphorylates tyrosines residues within the im |
| Immunogen | n/a |
| Other Names | [Tyrosine-protein kinase Lck; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK; LCK] |
| Gene, Accession # | [LCK], Gene ID: 3932, NCBI: NP_001036236.1, UniProt: P06239 |
| Catalog # | MBS9200166 |
| Price | $370 |
| Order / More Info | LCK Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yamaguchi H., et al. Nature 384:484-489(1996). Koga Y., et al. Eur. J. Immunol. 16:1643-1646(1986). Perlmutter R.M., et al. J. Cell. Biochem. 38:117-126(1988). Rouer E., et al. Gene 84:105-113(1989). Wright D.D., et al. Mol. Cell. Biol. 14:2429-2437(1994). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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