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Antigenic Specificity | Toll-like receptor 6 (TLR6) (NT) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (3) so the organism can respond to potential infection. TLR6 was first identified as a close homolog of TLR1, sharing 69% sequence identify (4). Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall part |
Immunogen | Immunogen: Rabbit polyclonal TLR6 antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human TLR6. |
Other Names | [TLR6 (IN): Toll-like receptor 6; CD286 antigen], [TLR6; TLR6; CD286] |
Gene, Accession # | [TLR6], Gene ID: 10333, NCBI: NP_006059.2, UniProt: Q9Y2C9 |
Catalog # | MBS395476 |
Price | $510 |
Order / More Info | Toll-like receptor 6 (TLR6) (NT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |