SRCIN1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SRCIN1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Direct ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for SRCIN1 detection. Tested with WB, IHC-P, Direct ELISA in Human; Mouse; Rat.Background: Using yeast 2-hybrid analysis, protein pull-down assays, and mutation analysis, it is showed that the first coiled-coil domain of rat Snip interacted with the N-terminal t-SNARE domain of Snap25 (600322). Biochemical studies demonstrated that Snip was tightly associated with rat brain cytoskeleton. Indirect immunofluorescence and confocal microscopy of rat PC12 pheochromocytoma cells revealed colocalization of Snip with Snap25 in the actin cytoskeleton, particularly in filopodia, lamellipodia, and neuritic extensions, including the tips. Overexpression of Snip or its Snap25-interacting domain inhibited c |
| Immunogen | Immunogen: E Coli-derived human SRCIN1 recombinant protein (Position: E189-E287). |
| Other Names | [SRC kinase signaling inhibitor 1; SNAP-25-interacting protein; SNIP; p130Cas-associated protein; p14 degree Cap; SRCIN1; KIAA1684; P140] |
| Gene, Accession # | [SRCIN1], Gene ID: 80725, NCBI: NP_079524.2, UniProt: Q9C0H9 |
| Catalog # | MBS1751511 |
| Price | $315 |
| Order / More Info | SRCIN1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Chin, L.-S., Nugent, R. D., Raynor, M. C., Vavalle, J. P., Li, L. SNIP, a novel SNAP-25-interacting protein implicated in regulated exocytosis. J. Biol. Chem. 275: 1191-1200, 2000. 2. Nagase, T., Kikuno, R., Hattori, A., Kondo, Y., Okumura, K., Ohara, O. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 7: 347-355, 2000. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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