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Antigenic Specificity | TRAF4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TRAF4 protein. Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract By similarity. Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.Tomasetto C.L., Genomics 28:367-376(1995).Miller H.G., Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.Cai C.L., Submitted (FEB-2005) to the |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human TRAF4. |
Other Names | [TNF receptor-associated factor 4; Cysteine-rich domain associated with RING and Traf domains protein 1; Malignant 62; RING finger protein 83; TRAF4] |
Gene, Accession # | [TRAF4], Gene ID: 9618, NCBI: NP_004286.2, UniProt: Q9BUZ4 |
Catalog # | MBS9413070 |
Price | $200, $255 |
Order / More Info | TRAF4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |