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Antigenic Specificity | HLA-DP/-DQ/-DR (MHC II) |
Clone | [CR3/43] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an i! chain (36kDa) and a ic chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six i! and ten ic chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a crit |
Immunogen | Immunogen: Cells from human tonsil Cellular Localization: Cell Surface |
Other Names | [HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5;] |
Gene, Accession # | [HLA-DP/-DQ/-DR], Gene ID: 3115, NCBI: NP_002112.3, UniProt: P04440 |
Catalog # | MBS4380017 |
Price | $190, $340, $340 |
Order / More Info | HLA-DP/-DQ/-DR (MHC II) Antibody from MYBIOSOURCE INC. |
Product Specific References | Gatter et al. 1982. J Clin Pathol. 35(11):1253-67. Gatter et al. 1982. Semin Oncol. 9(4):517-25. |