ITGB7 (C-term), 737-765 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | ITGB7 (C-term), 737-765 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This ITGB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 737-765 amino acids from the C-terminal region of human ITGB7. Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, a |
| Immunogen | n/a |
| Other Names | [Integrin beta-7; Gut homing receptor beta subunit; ITGB7] |
| Gene, Accession # | [ITGB7], Gene ID: 3695, NCBI: NP_000880.1, UniProt: P26010 |
| Catalog # | MBS9211415 |
| Price | $165, $370 |
| Order / More Info | ITGB7 (C-term), 737-765 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Cicala, C., et al. Proc. Natl. Acad. Sci. U.S.A. 106(49):20877-20882(2009) Pentikainen, U., et al. J. Mol. Biol. 393(3):644-657(2009) Lad, Y., et al. J. Biol. Chem. 283(50):35154-35163(2008) Monteiro, P., et al. Biochem. Biophys. Res. Commun. 358(2):442-448(2007) Le Floc'h, A., et al. J. Exp. Med. 204(3):559-570(2007) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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