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Antigenic Specificity | MTR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MTR4 antibody detects endogenous levels of total MTR4. Function: Component of exosome targeting complexes. Subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters (PubMed:27871484). May be involved in pre-mRNA splicing. Associated with the RNA exosome complex and involved in the 3'-proc |
Immunogen | Immunogen: A synthesized peptide derived from human MTR4 Subcellular Location: Nucleus, Nucleolus. Predicted Cross Reactivity: Pig, Bovine, Chicken Similarity: Pig (100%), Bovine (100%), Chicken (92%) |
Other Names | [2610528A15Rik; ATP dependent helicase SKIV2L2; Dob1; KIAA0052; MGC142069; mKIAA0052; Mtr4; superkiller viralicidic activity 2 like 2 (S. cerevisiae); Superkiller viralicidic activity 2 like 2] |
Gene, Accession # | [MTR4], Gene ID: 23517, NCBI: NP_056175.3, UniProt: P42285 |
Catalog # | MBS9608046 |
Price | $240, $280 |
Order / More Info | MTR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |