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Antigenic Specificity | Human CD10 |
Clone | [FR4D11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,k |
Format | Protein A purified |
Size | 0.1 mg, 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: CD10, also known as membrane metallo-endopeptidase, neutral endopeptidase(NEP), Neprilysin, or common acute lymphoblastic leukemia antigen(CALLA), is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably theamyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. This gene is localized to human chromosome 3 by study of somatic cell hybrids and regionalized the location to 3q21-q27 by in situ hybridization. By cDNA transfection analysis, CD10 is confirmed as a functional neutral endopeptidase of the type that has previously been called enkephalinase. CD10 has also been called atriopeptidase. Atriopeptid |
Immunogen | Immunogen: Raji cells. Subcellular Localization: Cell membrane; Single-pass type II membrane protein. |
Other Names | [Neprilysin; 3.4.24.11; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD10; MME; EPN], [MME] |
Gene, Accession # | [CD10], Gene ID: 4311, NCBI: NP_000893.2, UniProt: P08473 |
Catalog # | MBS179019 |
Price | $170, $465 |
Order / More Info | Human CD10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |