p63 (Squamous, Basal & Myoepithelial Cell Marker) Antibody from MYBIOSOURCE INC.

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Antigenic Specificityp63 (Squamous, Basal & Myoepithelial Cell Marker)
Clone[TP63/11]
Host SpeciesMouse
Reactive Specieshuman. mouse.
IsotypeIgG2a
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistology (Formalin-Fixed)
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DescriptionSpecificity: p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90%. Specificity for lung SqCC
ImmunogenImmunogen: Recombinant full-length human p63 protein Positive Control: HEK293 Cells or Prostate Carcinoma or Lung or bladder squamous cell carcinoma
Other Names[Amplified in squamous cell carcinoma (AIS); Chronic ulcerative stomatitis protein (CUSP); EEC3; Keratinocyte transcription factor KET; LMS; NBP; p40; P51/P63; p53 like transcription factor; p53-related protein p63; RHS; SHFM4; TAp63alpha; TP53CP; TP53L; TP63; TP73; TP73L; Transformation-related protein 63; Trp53rp1; Trp6; 3; Tumor protein 63; Tumor protein p53-like; tumor protein p73-like]
Gene, Accession #[TP63], Gene ID: 8626, NCBI: NP_001108450.1, UniProt: Q9H3D4
Catalog #MBS4380729
Price$190, $340, $340
Order / More Infop63 (Squamous, Basal & Myoepithelial Cell Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesYang A, et al. Mol Cell. 1998; 2(3):305-16.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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