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Antigenic Specificity | ITGAX/CD11c (N-term), 246-274 |
Clone | [428CT12.2.6.4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ITGAX/CD11c antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human ITGAX/CD11c. This gene encodes the integrin alpha X chain protein.Integrins are heterodimeric integral membrane proteins composed ofan alpha chain and a beta chain. This protein combines with thebeta 2 chain (ITGB2) to form a leukocyte-specific integrin referredto as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2complex seems to overlap the properties of the alpha M beta 2integrin in the adherence of neutrophils and monocytes tostimulated endothelium cells, and in the phagocytosis of complementcoated particles. |
Immunogen | n/a |
Other Names | [Integrin alpha-X; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150; CD11c; ITGAX; CD11C] |
Gene, Accession # | [ITGAX], Gene ID: 3687, NCBI: NP_000878.2, UniProt: P20702 |
Catalog # | MBS9200317 |
Price | $370 |
Order / More Info | ITGAX/CD11c (N-term), 246-274 Antibody from MYBIOSOURCE INC. |
Product Specific References | Van Brussel, I., et al. J. Immunol. Methods 362 (1-2), 168-175 (2010) : Chen, X., et al. Proc. Natl. Acad. Sci. U.S.A. 107(33):14727-14732(2010) Lindsay, R.W., et al. J. Immunol. 185(3):1513-1521(2010) Kraus, T.S., et al. Am. J. Clin. Pathol. 134(2):271-277(2010) Quist, S.R., et al. Acta Derm. Venereol. 90(4):429-430(2010) |