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Antigenic Specificity | Human Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Acts as a regulator of RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. In addition to peptidyl-lysine 5-dioxygenase activity, may act as an RNA hydroxylase, as suggested by its ability to bind single strand RNA. Also acts as an arginine demethylase which demethylates histone H3 at 'Arg-2' (H3R2me) and histone H4 at 'Arg-3' (H4R3me), thereby playing a role in histone code. However, histone arginine demethylation may not constitute the primary activit |
Immunogen | Immunogen: Recombinant humanBifunctional arginine demethylase and lysyl-hydroxylase JMJD6 protein (1-320aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-32740 / sc-11635 / sc-11632 / sc-11633 / sc-11366 |
Other Names | [Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; Jumonji domain-containing protein 6; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine receptor; Protein PTDSR; JMJD6; KIAA0585; PTDSR], [JMJD6; JMJD6; PSR; PTDSR; PTDSR1; KIAA0585; PTDSR; Protein PTDSR] |
Gene, Accession # | [JMJD6], Gene ID: 23210, NCBI: NP_001074930.1, UniProt: Q6NYC1 |
Catalog # | MBS1497129 |
Price | $120, $160 |
Order / More Info | Human Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |