SNAP25 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SNAP25 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The 25 kDasynaptosome-associated protein (SNAP25) is a target membrane soluble, N-ethylmaleimide-sensitive factor attachment protein receptor (t-SNARE) that is found on neuronal presynaptic membranes. SNAP25 forms a core complex with the SNARE proteins syntaxin and synaptobrevin to mediate synaptic vesicle fusion with the plasma membrane during Ca2+-dependent exocytosis (1). This complex is responsible for exocytosis of the neurotransmitter gamma-aminobutyric acid (GABA). Neurotransmitter release is inhibited by proteolysis of SNAP25 by botulinum toxins A and E (2). SNAP25 plays a secondary role as a Q-SNARE involved in endosome fusion; the protein is associated with genetic susceptibility to attention-deficit hyperactivity disorder (ADHD) |
| Immunogen | Immunogen: Recombinant protein of human SNAP25 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [SNAP25; FLJ23079; RIC-4; RIC4; SEC9; SNAP; SNAP-25; bA416N4.2; dJ1068F16.2] |
| Gene, Accession # | [SNAP25], Gene ID: 6616, NCBI: NP_001309831.1, UniProt: P60880 |
| Catalog # | MBS8506012 |
| Price | $310 |
| Order / More Info | SNAP25 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Salaun, C. et al. (2004) BiochimBiophysActa 1693, 81-9. 2. Fan, H.P. et al. (2006) J BiolChem 281, 28174-84. 3. Aikawa, Y. et al. (2006) MolBiol Cell 17, 2113-24. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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