Edit |   |
---|---|
Antigenic Specificity | OPA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of OPA1 protein. The protein encoded by OPA1 gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human OPA1 protein |
Other Names | [Rabbit OPA1; Dynamin-like 120 kDa protein, mitochondrial; Optic atrophy protein 1] |
Gene, Accession # | [OPA1], Gene ID: 4976, NCBI: NP_056375.2, UniProt: O60313 |
Catalog # | MBS9710197 |
Price | $130, $220, $325 |
Order / More Info | OPA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |