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Antigenic Specificity | MED23 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1.2mg/mL |
Applications | Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively splic |
Immunogen | Immunogen: Synthetic peptide of human MED23 |
Other Names | [130 kDa transcriptional co activator; 133 kDa transcriptional co activator; Activator recruited cofactor 130 kDa component; Activator-recruited cofactor 130 kDa component; ARC 130; ARC130; Cofactor required for Sp1 transcriptional activation subunit 3 130kDa; Cofactor required for Sp1 transcriptional activation subunit 3 130kDa mediator; Cofactor required for Sp1 transcriptional activation subunit 3; CRSP 130; CRSP 130 kD subunit; CRSP 133; CRSP 3; CRSP complex subunit 3; CRSP130; CRSP133; CRSP3; CRSP3 protein; DKFZp434H0117; DRIP 130; DRIP130; HSur-2; KIAA1216; MED 23; Med23; MED23; Mediator complex subunit 23; Mediator of RNA polymerase II transcription subunit 23; MRT18; Protein sur-2 homolog; SUR 2; SUR2; Transcriptional co activator CRSP 130; Transcriptional co activator CRSP130; Transcriptional coactivator CRSP130; Vitamin D3 receptor interacting protein; Vitamin D3 receptor interacting protein complex 130 kDa component; Vitamin D3 receptor-interacting protein complex 130 kDa component] |
Gene, Accession # | [MED23], Gene ID: 9439, NCBI: NP_001257450.1, UniProt: Q9ULK4 |
Catalog # | MBS2559752 |
Price | $110, $150, $225 |
Order / More Info | MED23 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |