MC4R Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MC4R |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MC4R Antibody: The melanocortin-4 receptor (MC4R) is a member of the superfamily of seven transmembrane G-protein coupled receptors that are involved in multiple signal transduction pathways including the cAMP and MAPK signaling pathways. It is thought that the melanocortin system modulates energy expenditure and insulin sensitivity; activation of the MC4R results in the inhibition of c-Jun N-terminal kinase (JNK) activity and promotes insulin signaling. MC4R-null mice display maturity onset obesity characterized by hyperphagia, increased adiposity, hyperinsulinaemia and hyperleptinaemia, suggesting that like other obesity-linked genes such as FTO, PTER, and NPC1, MC4R is a potential candidate target for the treatment of obesity. |
| Immunogen | Immunogen: MC4R antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human MC4R. Buffer: MC4R Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [MC4R; Melanocortin receptor 4; MC4-R; melanocortin 4 receptor], [MC4R; MC4R; MC4-R] |
| Gene, Accession # | [MC4R], Gene ID: 4160, NCBI: NP_005903, UniProt: P32245 |
| Catalog # | MBS150230 |
| Price | $375 |
| Order / More Info | MC4R Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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