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Antigenic Specificity | MRP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat. |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Multidrug resistance-associated protein 4(ABCC4) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: ABCC4(Atp-binding cassette, subfamily c, member 4) also known as MRP4 or MOATB, is a protein that in humans is encoded by the ABCC4 gene. It belongs to a large family of transmembrane proteins involved in active transport of substrates out of cells. This gene is mapped to chromosome 13q32. ABCC4 acts as an independent regulator of intracellular cyclic nucleotide levels and as a mediator of cAMP-dependent signal transduction to the nucleus. The antiproliferative effect of ABCC4 inhibition was related to cAMP-dependent PKA activation and CREB phosphorylation. Pharmacologic inhibition |
Immunogen | Immunogen: E.coli-derived human MRP4 recombinant protein (Position: M1-P370). |
Other Names | [ABCC 4; ABCC4; ATP binding cassette sub family C (CFTR/MRP) member 4; ATP binding cassette sub family C member 4; ATP-binding cassette sub-family C member 4; bA464I2.1 (ATP binding cassette, sub-family C (CFTR/MRP) member 4); bA464I2.1; Canalicular multispecific organic anion transporter ABC superfamily; canalicular multispecific organic anion transporter EST170205; MOAT B; MOAT-B; MOATB; MRP 4; MRP/cMOAT related ABC transporter; MRP/cMOAT-related ABC transporter; MRP4_HUMAN; Multi specific organic anion transporter B; Multi-specific organic anion transporter B; Multidrug resistance associated protein 4; Multidrug resistance-associated protein 4; OTTHUMP00000018560; ATP-binding cassette, sub-family C (CFTR/MRP), member 4], [ABCC4; ABCC4; MRP4; MOATB; MOAT-B; MRP4; MOAT-B] |
Gene, Accession # | [ABCC4], Gene ID: 10257, NCBI: NP_001098985.1, UniProt: O15439 |
Catalog # | MBS177513 |
Price | $315 |
Order / More Info | MRP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |