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Antigenic Specificity | EXOSC2 |
Clone | [374] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | Protein A purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snoRNA and snRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. EXOSC2 is a non-catalytic component of the RNA exosome complex that has 3'->5' e |
Immunogen | Immunogen: Fusion protein of EXOSC2 |
Other Names | [EXOSC2; Exosome complex exonuclease RRP4; Exosome component 2; Homolog of yeast RRP4 (ribosomal RNA processing 4); 3' 5' exoribonuclease (RRP4); Homolog of yeast RRP4 (ribosomal RNA processing 4); 3'-5'-exoribonuclease; hRrp4p; OTTHUMP00000022370; OTTHUMP00000022371; OTTHUMP00000022372; OTTHUMP00000022373; OTTHUMP00000022374; p7; Ribosomal RNA processing protein 4; RRP4; Rrp4p] |
Gene, Accession # | [EXOSC2], Gene ID: 23404, NCBI: NP_001269637.1, UniProt: Q13868 |
Catalog # | MBS2541907 |
Price | $220, $290, $435 |
Order / More Info | EXOSC2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |