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Antigenic Specificity | VPS35 |
Clone | [7E4] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~92 kDa. Vacuolar Protein Sorter-35 (VPS35) is a component of the retromer complex, which is essential for endosome-to-Golgi retrieval of membrane proteins. VPS35 mutations such as D620N have been linked to Parkinson's Disease (PD) (1,2) and affect retromer function, protein homeostasis, and mitochondria (3). |
Immunogen | Immunogen: Full length recombinant human VSP35 Conjugate: Unconjugated |
Other Names | [Mouse Human VPS35 IgG2a; VPS35; Vacuolar protein sorting-associated protein 35; MEM3; PARK17; VPS35 retromer complex component; maternal-embryonic 3; vesicle protein sortin 35; TCCCTA00141; FLJ10752] |
Gene, Accession # | [VPS35], Gene ID: 55737, NCBI: NP_060676.2, UniProt: Q96QK1 |
Catalog # | MBS8005589 |
Price | $440 |
Order / More Info | VPS35 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Vilarino-Guell, C. et al. (2011) Am J Hum Genet 89:162-167. 2. Zimprich, A. et al. (2011) Am J Hum Genet 89:168-175. 3. Rahman, A.A., Morrison, B.E. (2019) Neurosci 401:1-10. |