CD59 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD59
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Size0.02 mL, 0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Flow Cytometry (FC/FACS)
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DescriptionThis gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, ha
ImmunogenSource Note: This monoclonal antibody is produced by immunizing animals with a polypeptide corresponding to CD59 protein.
Other Names[CD59 glycoprotein], [CD59; MIC11; MIN1; MIN2; MIN3; MSK21]
Gene, Accession #[CD59], Gene ID: 966, NCBI: NP_000602.1, UniProt: P13987
Catalog #MBS435198
Price$225, $350, $565
Order / More InfoCD59 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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