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Antigenic Specificity | BCL11A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total BCL11A protein. This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human BCL11A. |
Other Names | [EVI9; CTIP1; ZNF856; HBFQTL5; BCL11A-L] |
Gene, Accession # | [BCL11A], Gene ID: 53335, NCBI: NP_060484.2, UniProt: Q9H165 |
Catalog # | MBS9406632 |
Price | $255 |
Order / More Info | BCL11A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |