SOCS1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-SOCS1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | SOCS1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The Suppressor of cytokine signaling (SOCS) and cytokine-inducible SH2 proteins are a family of intracellular proteins which regulate the immune cell responses to cytokines. SOCS1 acts to suppress dendritic cell (DC) as well as T cell hyperactivation following cytokine signaling by inhibiting JAK tyrosine kinase, a kinase necessary for type I and II cytokine receptors to initiate signaling, by directly binding to the catalytic domain of the kinase. SOCS1 also possesses E3 ubiquitin protein ligase activity that results in the polyubiquitination of its target proteins and subsequent degradation by the proteosome. It is through this method that SOCS1 negatively regulates signaling by Toll-like receptors TLR2 and TLR4 by mediating the degradati |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 17 amino acid peptide from near the amino terminus of human SOCS1. |
| Other Names | [Suppressor of cytokine signaling 1, JAK-binding protein, JAB] |
| Gene, Accession # | [SOCS1], Gene ID: 8651, NCBI: CAB92528, UniProt: O15524 |
| Catalog # | MBS9412106 |
| Price | $320 |
| Order / More Info | SOCS1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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