MCM6 (Proliferation Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MCM6 (Proliferation Marker) |
| Clone | [MCM6/2999] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro. |
| Immunogen | Immunogen: Recombinant fragment (around aa 228-368) of human MCM6 protein (exact sequence is proprietary) |
| Other Names | [DNA replication licensing factor MCM6; MCM6 minichromosome maintenance deficient 6; MIS5 homolog; p105MCM] |
| Gene, Accession # | [MCM6], Gene ID: 4175, NCBI: Q14566.1, UniProt: Q14566 |
| Catalog # | MBS4381080 |
| Price | $190, $340, $340 |
| Order / More Info | MCM6 (Proliferation Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Koonin, E.V. 1993. Nucleic Acids Res. 21: 2541-2 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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