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Antigenic Specificity | MRGBP (Center), 46-75 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.48 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MRGBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the Central region of human MRGBP. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, a |
Immunogen | n/a |
Other Names | [MRG/MORF4L-binding protein; MRG-binding protein; Up-regulated in colon cancer 4; Urcc4; MRGBP; C20orf20] |
Gene, Accession # | [MRGBP], Gene ID: 55257, NCBI: NP_060740.1, UniProt: Q9NV56 |
Catalog # | MBS9203863 |
Price | $165, $370 |
Order / More Info | MRGBP (Center), 46-75 Antibody from MYBIOSOURCE INC. |
Product Specific References | Yamaguchi, K., et al. Br. J. Cancer 102(2):325-331(2010) Cai, Y., et al. J. Biol. Chem. 280(14):13665-13670(2005) Cai, Y., et al. J. Biol. Chem. 278(44):42733-42736(2003) Deloukas, P., et al. Nature 414(6866):865-871(2001) |