Human MIS Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman MIS
Clone[7H26]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionMuI?llerian inhibiting substance (MIS), also named antiMuI?llerian hormone (AMH), is a tissuespecific TGFbeta superfamily growth factor. Its expression is restricted to the Sertoli cells of fetal and postnatal testis, and to the granulosa cells of postnatal ovary. The human MIS gene encodes a 553 amino acid residue (aa) prepropeptide containing a signal a sequence (1-24), a proregion (25-455), and the carboxylterminal bioactive protein (446-553). MIS is synthesized and secreted as a disulfidelinked homodimeric proprotein. Proteolytic cleavage is required to generate the Nterminal pro region and the C-terminal bioactive protein, which remain associated in a noncovalent complex. Recombinant C-terminal MIS has been shown to be bioactive. Howev
ImmunogenAntibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of MIS.
Other Names[AMH; MIF; MIS], [AMH; AMH; MIF; MIS; MIF; AMH; MIS]
Gene, Accession #[MIS], Gene ID: 268, NCBI: NP_000470.2, UniProt: P03971
Catalog #MBS690011
Price$490
Order / More InfoHuman MIS Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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