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Antigenic Specificity | BTK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Multiple isoforms of BTK are known to exist. BTK Antibody: Bruton's tyrosine kinase (BTK) was initially identified as a member of the src family for protein-tyrosine kinases that was involved in X-linked agamma-globulinaemia, and has since been shown to involved in a number of signaling pathways in hemapoietic lineage. It has recently been shown to interact with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9. The TLRs are critical molecules in both the innate and adaptive immunity and can recognize diverse microbial pathogens. BTK has also been shown to interact with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting that BTK is involved in lipo |
Immunogen | Immunogen: BTK antibody was raised against a synthetic peptide corresponding to 16 amino acids near the amino-terminus of human BTK. Buffer: BTK Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [BTK; AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1; Tyrosine-protein kinase BTK; Agammaglobulinemia tyrosine kinase; Bruton agammaglobulinemia tyrosine kinase], [BTK; BTK; AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1; AGMX1; ATK; BPK; ATK; BPK] |
Gene, Accession # | [BTK], Gene ID: 695, NCBI: Q06187.3, UniProt: Q06187 |
Catalog # | MBS150593 |
Price | $375 |
Order / More Info | BTK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |