HSP60 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | HSP60 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for 60 kDa heat shock protein, mitochondrial(HSPD1) detection. Tested with WB, IHC-P, ICC in Human, Mouse, Rat. Background: HSP60 is a member of the chaperonin class of protein factors, which include the Escherichia coli groEL protein and the Rubisco subunit-binding protein of chloroplasts. It acts as a costimulator of human regulatory CD4-positive/CD25 -positive T cells, which inhibit lymphoproliferation and IFNG and TNF secretion by CD4-positive and CD8-positive T cells. HSP60 enhances Treg activity via TLR2, leading to activation of an intracellular signaling cascade that included p38, as well as inhibition of ERK phosphorylation. Suppression of target T cells is mediated by both cell-to-cell c |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of rat HSP60 (503-516aa YDAMLGDFVNMVEK), different from the related human sequence by one amino acid. |
| Other Names | [60 kDa heat shock protein, mitochondrial; heat shock 60kDa protein 1(chaperonin); 60 kDa chaperonin; 60 kDa heat shock protein mitochondrial; 60 kDa heat shock protein, mitochondrial; CH60_HUMAN; Chaperonin 60; Chaperonin; Chaperonin, 60-KD; CPN 60; CPN60; fa04a05; GROEL; GroEL Homolog; Heat shock 60kD protein 1 chaperonin; Heat shock 60kDa protein 1; Heat shock protein 1(chaperonin); Heat Shock Protein 60; Heat shock protein 65; HLD4; Hsp 60; HSP 65; HSP-60; HSP60; HSP65; HSPD 1; HSPD1; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein; Short heat shock protein 60 Hsp60s1; Spastic paraplegia 13; SPG 13; SPG13], [Hspd1; Hspd1; Hsp60; Hspd1-30p; Hsp60; CPN60; HSP-60; Hsp60] |
| Gene, Accession # | [HSPD1], Gene ID: 63868, NCBI: P63039.1, UniProt: P63039 |
| Catalog # | MBS175435 |
| Price | $315 |
| Order / More Info | HSP60 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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