TNFAIP3/A20 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTNFAIP3/A20
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB)
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DescriptionUbiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. In cooperation with TAX1BP1 promotes disassembly of E2-E3 ubiquitin protein ligase complexes in IL-1R and TNFR-1 pathways; affected are at least E3 ligases TRAF6, TRAF2 and BIRC2, and E2 ubiquitin-conjugating enzymes UBE2N and UBE2D3. In cooperation with TAX1BP1 promotes ubiquitination of UBE2N and
ImmunogenImmunogen: A synthesized peptide derived from human TNFAIP3. Subcellular Localization: Cytoplasm. Nucleus. Lysosome.
Other Names[Tumor necrosis factor alpha-induced protein 3; TNF alpha-induced protein 3; 3.4.19.12; 6.3.2.-; OTU domain-containing protein 7C; Putative DNA-binding protein A20; Zinc finger protein A20; A20p50; A20p37; TNFAIP3; OTUD7C], [TNFAIP3]
Gene, Accession #[TNFAIP3/A20], Gene ID: 7128, NCBI: NP_001257436.1, UniProt: P21580
Catalog #MBS179203
Price$160, $340, $340
Order / More InfoTNFAIP3/A20 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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