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Antigenic Specificity | RAN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RAN antibody detects endogenous levels of total RAN. Description: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.Function: GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs (PubMed:10400640, PubMed:8276887, PubMed:8896452, PubMed:8636225, PubMed:8692944, PubMed:9351834, PubMed:9428644, PubMed:9822603, PubMed |
Immunogen | Immunogen: A synthesized peptide derived from human RAN Subcellular Location: Nucleus. Cytoplasm. Melanosome. Becomes dispersed throughout the cytoplasm during mitosis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Tissue Specificity: Expressed in a variety of tissues. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Sheep, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (83%), Bovine (100%), Sheep (100%), Dog (100%), Chicken (92%), Xenopus (91%) |
Other Names | [Androgen receptor associated protein 24; Androgen receptor-associated protein 24; ARA 24; ARA24; Gsp1; GTP binding nuclear protein RAN; GTP-binding nuclear protein Ran; GTPase Ran; Guanosine triphosphatase Ran; LPS; OK/SW-cl.81; ran; RAN member RAS oncogene family; RAN_HUMAN; RanGTPase; Ras like protein TC4; Ras related nuclear protein; Ras-like protein TC4; Ras-related nuclear protein; RASL2 8; TC 4; TC4] |
Gene, Accession # | [RAN], Gene ID: 5901, NCBI: NP_001287725.1, UniProt: P62826 |
Catalog # | MBS9601539 |
Price | $240, $280 |
Order / More Info | RAN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |