Phospho- JAK2 (pTyr 1007/1008) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Phospho- JAK2 (pTyr 1007/1008) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Phospho- JAK2 (pTyr 1007/1008) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes JAK2 with dual phosphorylated sites of Tyr1007/1008. It does not cross-react with nonphosphospecific peptide. The Janus tyrosine kinase family is consists of four members, JAK1, JAK2, JAK3 and Tyk2. Upon the cytokine ligand binding to its the receptors, the dimerization of the receptors occurs followed by phosphorylation of the receptors. The phosphorylation of receptors recruites the tyrosine kinase physically associated to the dimerized receptors, and phosphorylate the kinase, thus activates the signal transducer and activator of thranscription (STAT1, 3, 5) and the other signal proteins. |
| Immunogen | Antigen Preparation: A synthetic peptide surrounding to the epitope -EYYK- with dual phosphorylation sites at Tyr1007 and Tyr1008 of JAK2 from human, mouse and rat origins. |
| Other Names | [Rabbit Phospho-JAK2; phosphospecific-Janus Kinase 2], [JAK2; JAK2; JTK10] |
| Gene, Accession # | [JAK2 (pY1007/Y1008)], Gene ID: 3717, NCBI: NP_004963.1, UniProt: O60674 |
| Catalog # | MBS462107 |
| Price | $285 |
| Order / More Info | Phospho- JAK2 (pTyr 1007/1008) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yogev,O., et al. SHP-2 regulates SOCS-1-mediated Janus kinase-2 ubiquitination/degradation downstream of the prolactin receptor. J. Biol. Chem. 278 (52), 52021-52031 (2003) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies