Edit |   |
---|---|
Antigenic Specificity | Bmf |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bmf Antibody: Apoptosis is related to many diseases and development. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3-only proteins, including Bad, Bid, Bik, Hrk, Bim, Noxa, and PUMA, form a growing subclass of the Bcl-2 family. A novel BH3-only protein was recently identified in human and mouse and designated Bmf (for Bcl-2-modifing factor). The BH3 domain in Bmf is required both for binding to Bcl-2 proteins and for triggering apoptosis. In healthy cells, Bmf associates with the dynein light chain 2 (DLC2) component of the myosin V motors and is sequestered by the cell's actin cytoskeleton. Disruption of the actin cyto |
Immunogen | Immunogen: Bmf antibody was raised with a synthetic peptide corresponding to 15 amino acids near the amino terminus of human Bmf. Buffer: Bmf Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Bmf; Bcl-2-modifying factor; Bcl2 modifying factor], [BMF; BMF] |
Gene, Accession # | [BMF], Gene ID: 90427, NCBI: NP_277038, UniProt: Q96LC9 |
Catalog # | MBS151560 |
Price | $375 |
Order / More Info | Bmf Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |