GCLC Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | GCLC |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Glutamate--cysteine ligase catalytic subunit(GCLC) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: GCLC, Glutamate--cysteine ligase catalytic subunit, is an enzyme that in humans is encoded by the GCLC gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. The gene encoding the catalytic subunit encodes a protein of 367 amino acids with a calculated molecular weight of 72.773 kDa and maps to chromosome 6p12.1. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human GCLC (6-23aa GSPLSWEETKRHADHVRR), different from the related rat and mouse sequences by one amino acid. |
| Other Names | [Glutamate--cysteine ligase catalytic subunit; glutamate-cysteine ligase, catalytic subunit; EC 6.3.2.2; Gamma ECS; Gamma GCS; Gamma glutamylcysteine synthetase; Gamma-ECS; Gamma-glutamylcysteine synthetase; GCL; GCLC; GCLM; GCS; GCS Heavy Chain; GLCL; GLCLC; GLCLR; Glutamate cysteine ligase catalytic subunit; Glutamate cysteine ligase(gamma glutamylcysteine synthetase) regulatory(30.8kD); Glutamate cysteine ligase catalytic subunit; Glutamate cysteine ligase modifier subunit; Glutamate cysteine ligase regulatory protein; Glutamate cysteine ligase regulatory subunit; Glutamate--cysteine ligase catalytic subunit; GSC light chain; GSH1_HUMAN], [GCLC; GCLC; GCL; GCS; GLCL; GLCLC; GLCL; GLCLC] |
| Gene, Accession # | [GCLC], Gene ID: 2729, NCBI: P48506.2, UniProt: P48506 |
| Catalog # | MBS175561 |
| Price | $315 |
| Order / More Info | GCLC Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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